Huberman Lab: AMA #5: Intrusive Thoughts, CGMs, Behavioral Change, Naps & NSDR

Scicomm Media Scicomm Media 3/24/23 - Episode Page - 24m - PDF Transcript

Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools

for everyday life.

I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford

School of Medicine.

Today is an Ask Me Anything episode, or AMA.

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And now without further ado, I will answer your questions, and as always, I will strive

to be as thorough as possible, as clear as possible, and as concise as possible.

Our first question is about abstaining from thoughts.

And in answering this question, we're going to skirt right up against a topic that I've

covered before on the podcast, which is obsessive compulsive disorder, which is a very serious

disorder.

I mean, it can have a range of severity, but people with true OCD suffer a lot from obsessions.

These are intrusive thoughts and compulsions, which are the behaviors typically associated

with those thoughts.

I think it's really important that we define OCD really clearly so that we can make sure

that we're talking about intrusive thoughts and the desire to abstain from thoughts versus

OCD and where there might be some overlap there.

The functional definition of OCD that really pertains to the disorder, obsessive compulsive

disorder, OCD, as opposed to, you know, we call people neurotic, or we say, you have

OCD or I'm so OCD about this or OCD about that, that's become kind of common use of

the acronym OCD, but true OCD is a situation in which the engaging in a particular compulsive

behavior does not serve to reduce the intensity or the frequency of the obsessions.

In fact, it makes it worse.

Okay.

So the typical thing that we hear these days is, oh, you're so OCD or he's so OCD or she's

so OCD or I'm so OCD.

Now if someone is OCD in that sense, okay, so not the clinical disorder, but OCD in the

sense that, you know, they're really clean, they're really fastidious, they need everything

perfect.

However, that person can achieve some level of calm and comfort that's fairly long lasting,

if everything's clean and perfect, well, then that's not obsessive compulsive disorder.

This is really important to understand as we venture into answering the question about

intrusive thoughts and the desire to abstain from certain thoughts.

A person with true OCD will keep cleaning and cleaning or washing their hands or arranging

things at perfect right angles, but the more they do it, the more their anxiety goes up.

A person who has more typical, gosh, we don't really even have a language for this nowadays,

unfortunately, but the sort of person that's extremely particular, they need things a certain

way and they're very driven to resolve things and do things to make sure that things are

done in a certain way or handled in a certain way.

Well, if that person can experience relief from engaging in, let's say, exercise or from

cleaning, right, you'd say, you're so OCD about exercise, well, but if exercising for

an hour or even two hours in the morning makes somebody really calm the rest of the day and

they don't need to exercise, well, then they're not necessarily true OCD, they don't necessarily

have a disorder related to exercise.

However, if they're exercising for two hours in the morning and then they find they can't

concentrate on other things and their desire to exercise just increases and increases and

becomes intrusive for them disrupting their quality of life throughout the day, well,

then that's falling under the umbrella of what we would call a true disorder.

Okay, so we want to highlight that because the question is about a desire to abstain from

thoughts and the question is in your discussion with Dr. Anna Lemke and I should just mention

Dr. Anna Lemke is the director of our dual diagnosis addiction clinic at Stanford University

School of Medicine. She's the author of this incredible book, Dopamine Nation that I think

everybody should read. I do believe everyone should read that book. So important for the

addict and non addict alike because it deals with basically the state of our life nowadays.

We're living in this dopamine rich world where we can quickly become dopamine depleted, which

is terrible leads to depression in addition to things like addiction in some folks, etc.

Anna was a guest on the podcast. You can find her episode at hubermanlab.com just put Anna.

I think she's the only guest we've had thus far whose name is Anna. So it'll just pop

up there. The entire website is searchable. But if you want to listen to that episode

or watch that episode, you can access it at hubermanlab.com. The question is, in your

discussion with Dr. Anna Lemke, you were talking about abstaining from people's drug of choice

for 30 days to reset the dopamine reward pathway. And indeed that is the prescriptive that Dr.

Anna Lemke gives for most all addictions and for people that are suffering from mild or

even severe depression related to dopamine seeking behaviors, social media, video games,

sex, food, etc. However, of course, in the instance of food or in some other addictions,

you can't abstain for 30 days, right? That would be terrible to abstain for food for

30 days. I'm sure people have done it, but it is not healthy to do certain things like

alcohol and drugs. People can abstain for 30 days in efforts to never go back to them

again. There are cases of severe alcohol or opiate dependence where people can't go cold

turkey or they risk dying. So there they need to really work with a physician. But the 30

day reset of the dopamine system is something that's very real and that pertains to most

people. That is, it's going to be very effective for most people struggling with either behavioral

what are sometimes called process addictions or other types of addictions, including substance

abuse issues. The question continues, you said you were going to ask Anna how to abstain

if your drug of choice is a thought or narrative as opposed to a substance or behavior. The

question continues as far as I can tell your discussion with Anna moved on before you asked

her the question, would you be able to discuss strategies for abstaining from addictive thoughts

and narratives? Okay, so let's talk about intrusive thoughts and let's start off by

asking ourselves what is a thought? Okay, in the realm of neurobiology, we have sensations

which are the processes by which our neurons nerve cells convert light photons, sound waves,

touch mechanical pressure, etc. into electrical signals and chemical signals that head into

our nervous system, including our brain, and then our brain, at least we think make sense

of them and help us navigate the world that we're in. Okay, so the sensation part is a

pure transformation of mechanical information or in some cases chemical information like

smell chemicals, literally volatile chemicals floating around in the world or brought into

your nose and your neurons in your olfactory bulb convert those into electrical and chemical

signals that your brain can understand. Perceptions are your idea of what those signals

out in the world are, either because you're paying attention to them, or for some other

reason, you decide that stop sign in front of you is red and that the sign behind it

is white and that the sky is blue or cloudy. Those are perceptions. Okay, so we have sensations

and perceptions. Then we have emotions, which are these things that include the mind and

body that are related to neuromodulators like dopamine, serotonin, etc. Although those

chemicals do other things as well. And then of course, we have behaviors, actions, everything

from me moving my pen on a piece of paper to walking, running, etc. Thoughts are a fifth

category of neural functioning that we really need to define, but that doesn't have as strict

a definition as sensations, perceptions, or feeling or action. But thoughts are real,

right? We all know this thoughts are real. And one way that we can define thoughts is

that thoughts are perceptions that include data from the past, present or future, okay,

or combinations of past and present or present and future or future and past. Okay, I'm not

trying to give an overly complicated definition here, but if we are going to answer a question

about how to abstain from thoughts in a really direct and actionable way, we really need

to address what our thoughts. So thoughts are perceptions that are generated internally,

right? We don't need any external sensation in order to have a thought, we can close our

eyes, we could be in sensory isolation for that matter, we can be floating with no gravity,

and we can have a thought. Thoughts tend to run pretty much automatically in the background

all the time. Some people refer to this as chatter in the back of our minds in a very

unstructured way. And then if we force our thoughts to be structured, because we decide

they need to be, or if something in our environment captures our perception, then our thoughts

tend to be structured. Let me give you an example. If I'm just walking around, if there

were a way in which we could broadcast my thoughts onto a screen, hope we wouldn't do that. But

those thoughts would be a mixture of semi-complete sentences and gibberish. However, if somebody

stops me and says, hi, good to see you, what are you doing today? And I start answering,

well, then my thoughts are suddenly being driven by an external stimulus, their question,

and some internal ideas, memory of who I am and what I'm doing that day, so past and

present and so on. And so thoughts become structured. So when we have a question about

how to abstain from thoughts, we need to be additionally specific and really pinpoint

that what we're trying to do is to abstain from thoughts we don't want, presumably either

because they are too repetitive and distracting, or because what's contained in those thoughts

is disturbing. Okay, this is important because it gives us two answers to the questions that

are highly divergent. One answer to the question of how to abstain from intrusive thoughts,

thoughts that we're addicted to, is if those thoughts are merely on loop all the time,

and we can't stop them, but the thoughts themselves aren't particularly disturbing.

So think about a song you can't get out of your head, or you keep recounting some event,

but the event itself isn't very disturbing. It's just intrusive because it's there. Well,

in that case, the data really point to trying to anchor your thoughts to some external stimulus.

So getting into action, getting into activities that really draw your attention away from

that thought. Now you may still hear it scrolling in the background. So you might be sitting

in class still hearing that loop of thoughts in the background. That's something that

over time ought to wane, it ought to disappear. If we try and bring more and more attention

to whatever it is that's in our environment, whatever it is that we happen to be learning

or doing physically, etc. Things like mindful meditation, doing a 10 or even just five minutes

a day practice of sitting with eyes closed or lying down with eyes closed and really

focusing on one's breath, focusing one's attention on that sometimes it's called the

third eye center. But in science, we'd say that just the region right behind the forehead,

you're directing your attention there has been shown to increase focus for singular

topics and can improve memory and do a bunch of other things as well. Those are data from

Dr. Wendy Suzuki's lab at New York University. She was a guest on the podcast as well. My

laboratory has run studies on mindful meditation as well. So what you're really trying to do

is learn how to focus better on one thing. And by focusing on that one thing, you focus

off these repetitive thoughts. Now I have a feeling that this question was asked and

that many people upvoted this question because the issue is in just thoughts that are intrusive

because they're there and on repeat, but because the thoughts themselves are actually

troubling. This could be recounting a trauma, someone harmed you, you observed something

that was disturbing, you felt wronged, you felt someone else was wronged, you can't

seem to get your mind off of something and your emotions tend to follow. And so it's

uncomfortable. I have a feeling this is the root of the question. In that case, the approach

is very different. What we know from essentially all of the quality scientific and clinical

studies is that those sorts of intrusive thoughts are very much like a trauma. Now we have to

be clear in defining what trauma is. I'll use the definition that Dr. Paul Conti, another

incredible guest that was on our podcast, a psychiatrist, Stanford, Harvard train psychiatrist,

I think one of the world's foremost leaders on the issue of trauma and psychiatry and

psychology generally, he defines trauma as an event or something that fundamentally changes

the way that your nervous system works, such that you function less adaptively going forward

from that event. Okay, so not every bad occurrence in your life is a trauma. That's good news.

The bad news is many people have traumas and traumas change the way that our nervous system

works so that we don't function as well as we could. So in that sense, intrusive thoughts

that are disturbing are in many ways traumas and are reinforcing that trauma. Now we know

that almost counterintuitively, in order to deal with trauma, you have to get very close

to that trauma. You don't have to re expose and I would hope you would not re expose yourself

to the very same trauma, but we know that one of the best ways to deal with traumas is to

get very clear about the narrative around those traumas. Now this can be done with a

therapist, ideally, but not everyone has access to therapy or can afford therapy. There's

a range of quality of therapists for that matter. So we're always referring to the desire

for people to do great therapy with really great meaning excellently trained people.

But it turns out that if you want to extinguish an intrusive thought, one of the best ways

to do that is to journal about that particular thought extensively. So rather than the earlier

strategy for intrusive thoughts where they're just on loop and intrusive because they're

on loop and present, but their content isn't disturbing. When a thought is disturbing

and intrusive, we know that it's very useful to script out as much detail about that particular

thought and the things around it as possible. Obviously you want to do this in a way that

is fairly structured. So you ideally would use complete sentences. So the reason for

doing that is that thoughts, as I mentioned earlier, can often be fragmentary. So they

pop up in our mind almost, we seemingly spontaneously, they're inhibiting our ability to focus or

be present to work or family or other things or sleep. Writing things down in a lot of

detail does seem to have this quality of both reducing the emotional load of whatever it

is that that thought is about, as well as diminishing the frequency of those intrusive

thoughts over time. So this is far and away different than the strategy I mentioned for

the other types of intrusive thoughts. And really it's far and away different from the

30 day abstinence approach that Dr. Anna Lemke was talking about for substance or behavioral

addictions. Now, of course, this process of abstaining from thoughts or removing the addictive

nature of certain thoughts can definitely take some time. So a good example there would

be superstitions. You know, I'll come clean here. And I've talked about this before on

a few podcasts that when I was in college, I developed a sort of knock on wood superstition.

Anytime I'd say something that I didn't want to happen or did want to happen, I'd say knock

on wood and I'd knock on wood. And then I started suppressing the behavior, most of

because it was a little embarrassing. And then I started just telling myself in my head,

knock on wood, knock on wood, knock on wood. And it was clearly a little bit of an OCD

hype thing. But again, OCD in air quotes here, I think it qualified as OCD in the sense

that the more I did it, the more I wanted to do it. So I needed to go cold turkey on

the thinking, but how can you go cold turkey on a thought? You couldn't. What I was told

to do and what worked very well for me was to just write down the worst possible outcome

that I was concerned about. So to really get close to the nature or the underlying basis

of that intrusive thought. And I raise this because a lot of times the intrusive thought

is not, okay, I'm thinking about a car accident or I'm thinking about a breakup or I'm thinking

about an exam that I have. That can be intrusive, but a lot of times it's some kind of nebulous

abstract set of words or ideas or images around something that happened that we saw or heard

or experienced. And by putting a lot of clear structure to what the thought is exactly and

to putting some thought and structure onto paper about what that pattern of not healthy

thinking relates to. People often achieve tremendous relief in a fairly short amount

of time, sometimes just in one session of writing it down. Sometimes they need to write

it down multiple times. What you're essentially trying to do with a intrusive thought or a

trauma of any kind is you're trying to turn a disturbing story that is a story that evokes

a lot of emotion and captures it kind of hijacks your nervous system into what is essentially

a known but repetitive and kind of old boring story where the emotional load has been depleted.

And there, of course, I have to highlight the fact that getting sufficient rapid eye

movement sleep, we also know is very important for removing the emotional load of traumatic

experiences and intrusive thoughts. So you really want to strive to get the best possible

sleep you can that includes sufficient rapid eye movement sleep. And we have multiple zero

cost resources for that at hubermanlab.com. We have the episode on master your sleep.

We have the episode on perfect your sleep. We have the toolkit for sleep, all of which

are time stamped and all of which can be accessed to completely zero cost to try and get your

sleep as good as possible, including lots of rapid eye movement sleep. So in order to

remove intrusive and addictive thoughts, ask yourself, is this OCD of the classic sense?

If it is, you should see a psychiatrist. They won't necessarily prescribe medication,

but there are tools for true OCD that that are very effective in many cases. And we did

the episode on OCD, which I invite you to listen to as well.

You want to ask yourself, are the thoughts disturbing or merely intrusive and repetitive?

If they're merely intrusive and repetitive, well, then learning to focus your attention

on other things and getting better at focusing on single things through an exercise like

mindfulness meditation can really help. And indeed, perhaps the best use of mindfulness

meditation is to improve your level of focus. It does have other benefits as well, but that's

going to be the major one that one will experience, even with these very short five or 10 minute

a day meditations, great data on that from the scientific literature. And then if those

intrusive thoughts are not only intrusive, but they're also disturbing, in that case,

you really want to put as much structure and thought, believe it or not, into what those

thoughts are really about, write them out on paper in complete sentences and maybe do

that multiple times until the underlying emotions related to those thoughts really start to diminish.

And by doing that, you're essentially doing your own form of trauma therapy for lack of

a better way to put it. And again, the data really point to the fact that getting close

to the specific details around those intrusive thoughts is going to be the best way to extinguish

them. Thank you for joining for the beginning of this Ask Me Anything episode to hear the

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Machine-generated transcript that may contain inaccuracies.

Welcome to a preview of the fifth Ask Me Anything (AMA) episode, part of the Huberman Lab Premium subscription.
The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.
Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium
Timestamps
(00:00:00) Introduction
(00:01:53) Strategies for Abstaining From Addictive Thoughts and Narratives
(00:21:07) Huberman Lab Premium

In the full AMA episode, we discuss:

Continuous Glucose Monitors (CGMs)

How to Build Good Habits Alongside a Partner Who Challenges Them?

Short Naps vs. Non-Sleep Deep Rest (NSDR) for Replenishing Energy and Dopamine


Title Card Photo Credit: Mike Blabac
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