Lex Fridman Podcast: #133 – Manolis Kellis: Biology of Disease

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:

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EPISODE LINKS:

Manolis Website: http://web.mit.edu/manoli/

Manolis Twitter: https://twitter.com/manoliskellis

Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA

Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis

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OUTLINE:

Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.

00:00 – Introduction

08:05 – Molecular basis for human disease

32:04 – Deadliest diseases

37:47 – Genetic component of diseases

46:38 – Genetic understanding of disease

1:02:25 – Unified theory of human disease

1:08:26 – Genome circuitry

1:33:29 – CRISPR

1:45:06 – Mitochondria

1:53:10 – Future of biology research

2:22:46 – The genetic circuitry of disease